| In the present investigation, total erythrocyte counts have been observed after nitrogen dioxide gas (50ppm) exposure in both the sexes of albino rats for one hour per day for 15 and 30 days. Nitrogen dioxide gas toxicity induces hypoxic polycythemia due to oxidative damage, which increases the number of red blood cells in both the sexes of albino rats. Male and female rats of equal size and weight (150-200g) were kept in standard laboratory conditions and grouped into three sets (I, II, & III) containing twelve rats each. Control set (I) was unexposed, Experimental set (II) was exposed to nitrogen dioxide gas (50ppm) and Experimental set (III) was exposed to nitrogen dioxide gas (50ppm) along with supplementation of vitamin C (5mg/rat) and E (2.5 mg/rat) in combination for one hour per day for 15 and 30 days. Total erythrocyte counts were declined after supplementation of vitamin C and E in combination in comparison to nitrogen dioxide gas exposed rats of both the sexes due to antioxidants defense mechanism. |